Indeed, ACN possess high antioxidant capacity and could play a key role in the prevention of oxidative stress by scavenging ROS and free radicals and modulating endogenous defense system, as demonstrated in several in vitro and in vivo studies (Zafra-Stone et al., 2007)
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However, these forms must be deacetylated inside cells to become biologically active, which may reduce immediate bioavailability compared to standard GSH
In cosmetic products, GHK-Cu has been studied in the context of tightening loose skin, improving elasticity and firmness, reducing fine lines, wrinkles, and hyperpigmentation, and enhancing overall skin appearance
doi: 10.1186/s12984-025-01695-9 131 LvKZhangSYaoZZhouCXuJ
